NFKBIL2 antibody

Catalog No. ABIN2427657

Product Details anti-NFKBIL2 Antibody

Target: NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFKBIL2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Antigen affinity purification

Immunogen: Recombinant protein of human TONSL

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C/-80 °C

Storage Comment: Store at -20°C (regular) and -80°C (long term).

Target Details for NFKBIL2

Target: NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))

Alternative Name: TONSL (NFKBIL2 Products)

Synonyms: IKBR antibody, NFKBIL2 antibody, 2810439M11Rik antibody, Nfkbil2 antibody, im:7145273 antibody, nfkbil2 antibody, tonsl antibody, tonsoku like, DNA repair protein antibody, tonsoku-like, DNA repair protein antibody, TONSL antibody, Tonsl antibody, tonsl antibody

Background: The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
Synonyms: IKBR, NFKBIL2

Pathways: Maintenance of Protein Location