Exonuclease 1 antibody (Internal Region)

Catalog No. ABIN238661

Product Details anti-Exonuclease 1 Antibody

Target: Exonuclease 1 (EXO1)

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Exonuclease 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: EXO1

Sequence: HRNYSPRPES GT

Specificity: This antibody is expected to recognise all three reported isoforms (NP_003677.3, NP_006018.3 and NP_569082.1)

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Immunogen: Peptide with sequence C-HRNYSPRPESGT, from the internal region of the protein sequence according to NP_003677.3, NP_006018.3, NP_569082.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 90 kDa band observed in lysates in cell lines HEK293 and A549 (calculated MW of 89.1 kDa according to NP_003677.3). Recommended concentration: 0.2-0.5 μg/mL. An additional band of unknown identity was also consistently observed at 38k

Peptide ELISA: antibody detection limit dilution 1:64000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for Exonuclease 1

Target: Exonuclease 1 (EXO1)

Alternative Name: EXO1 (EXO1 Products)

Synonyms: HEX1 antibody, hExoI antibody, 5730442G03Rik antibody, Msa antibody, EXO1 antibody, exoi antibody, fc16e04 antibody, wu:fc16e04 antibody, zgc:55521 antibody, exonuclease 1 antibody, hypothetical protein antibody, exonuclease I Exo1 antibody, RNA exonuclease antibody, exonuclease 1 S homeolog antibody, EXO1 antibody, Y17G7B.12 antibody, SJAG_01832 antibody, PAS_chr1-1_0377 antibody, Exo1 antibody, exo1 antibody, exo1.S antibody, LOC100338764 antibody

Background: EXO1, exonuclease 1, HEX1, hExoI, rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1

Gene ID: 9156

NCBI Accession: NP_003677, NP_006018, NP_569082

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response