CEACAM20 antibody

Catalog No. ABIN238330

Product Details anti-CEACAM20 Antibody

Target: CEACAM20 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 20 (CEACAM20))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEACAM20 antibody is un-conjugated

Application: Flow Cytometry (FACS), Cell-ELISA (cELISA)

Purification: Protein G

Immunogen: genetic immunisation with cDNA encoding human CEACAM20

Clone: HT-12D8

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C

Storage Comment: short term: 2 °C - 8 °C, long term: -20 °C

Target Details for CEACAM20

Target: CEACAM20 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 20 (CEACAM20))

Alternative Name: CEACAM20 (CEACAM20 Products)

Synonyms: UNQ9366 antibody, 9130012D09Rik antibody, carcinoembryonic antigen related cell adhesion molecule 20 antibody, carcinoembryonic antigen-related cell adhesion molecule 20 antibody, CEACAM20 antibody, Ceacam20 antibody

Background: CEA-related cell adhesion molecule 20 (CEACAM20) belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a putative glycoprotein which is membrane-bound via a transmembrane domain. The CEACAM20 protein contains a single N domain followed by 4 immunoglobulin-like A (A1, A2) and B (B1, B2) domains. Expression of CEACAM20 can be found in tissues of prostate, testis, duodenum and small intestine with highest expression in prostate. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. High expression of CEACAM20 in tissue of prostate carcinoma and in prostate carcinoma cell lines suggest that CEACAM20 can be used as a tumor marker.

UniProt: Q6UY09