RSL1D1 antibody (Internal Region)

Catalog No. ABIN233832

Product Details anti-RSL1D1 Antibody

Target: RSL1D1 (Ribosomal L1 Domain Containing 1 (RSL1D1))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RSL1D1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an sequence of human PBK1.

Isotype: IgG

Application Details

Application Notes: This affinity purified antibody has been tested for use in ELISA, immunoprecipitation, immunofluorescence microscopy and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 75 kDa in size corresponding to PBK1 by western blotting in the appropriate cell lysate or extract.  This antibody is capable of detecting both over-expressed and endogenous PBK1. For immunofluorescence microscopy, fix cells with methanol.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for RSL1D1

Target: RSL1D1 (Ribosomal L1 Domain Containing 1 (RSL1D1))

Alternative Name: PBK1 (RSL1D1 Products)

Synonyms: DKFZp468I212 antibody, CSIG antibody, PBK1 antibody, UTP30 antibody, 2410005K20Rik antibody, C76439 antibody, pBK1 antibody, Csig antibody, ribosomal L1 domain containing 1 antibody, ribosomal L1 domain containing 1 L homeolog antibody, RSL1D1 antibody, rsl1d1 antibody, PTRG_05078 antibody, rsl1d1.L antibody, Rsl1d1 antibody

Background: This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. PBK1 protein (also known as Ribosomal L1 domain-containing protein 1, cellular senescence-inhibited gene protein, and CATX-11) was isolated from highly invasive first trimester trophoblast cells and has been proposed to regulate their naturally occurring invasive behavior (Huch et al., 1998). PBK1 was also found to be over-expressed in non-small-cell lung cancer (NSCLC) cells (Petroziello et al., 2004).  A recent study suggests that PBK1 may up-regulate the urokinase-type plasminogen activator (uPA) gene, which plays an important role in cellular matrix degradation and
Synonyms: CATX11 antibody, Cellular senescence inhibited gene protein antibody, CSIG antibody, L12 antibody, Ribosomal L1 domain containing 1 antibody

Gene ID: 26156

UniProt: O76021