TMBIM1 antibody (N-Term)

Catalog No. ABIN233805

Product Details anti-TMBIM1 Antibody

Target: TMBIM1 (Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMBIM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to the amino terminus of human TMBIM1 protein.
Immunogentype:Recombinant

Isotype: IgG

Application Details

Application Notes: This protein A purified antibody has been tested for use in ELISA and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 35 kDa in size corresponding to TMBIM-1 by western blotting in the appropriate cell lysate or extract.  To date this antibody has shown the ability to recognize over-expressed TMBIM1 but not endogenous protein.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-TMBIM1 antibody (ABIN233805)

Shukla, Fujita, Xiao, Liao, Garfield, Srinivasula: "A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface." in: Apoptosis : an international journal on programmed cell death, (2010) (PubMed).

Target Details for TMBIM1

Target: TMBIM1 (Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1))

Alternative Name: TMBIM1 (TMBIM1 Products)

Background: This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. TMBIM1 (Transµembrane BAX inhibitor µotif-containing protein 1) is a member of the 7 TMS (7 transmembrane domains) family of receptors known to mediate the activation of various transcription factors. TMBIM1 is identified as a novel modulator of NF-kB activation.  A drosophila homolog of this protein (dNMDA1 with 40% homology to hTMBIM1) is reported to be unregulated during aging and oxidative stress.
Synonyms: Putative uncharacterized protein TMBIM1

Gene ID: 64114, 50593008

UniProt: Q969X1