TMBIM1 antibody (N-Term)

Catalog No. ABIN233805

Product Details anti-TMBIM1 Antibody

Target: TMBIM1 (Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMBIM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to the amino terminus of human TMBIM1 protein.
Immunogentype:Recombinant

Isotype: IgG

Application Details

Application Notes: This protein A purified antibody has been tested for use in ELISA and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 35 kDa in size corresponding to TMBIM-1 by western blotting in the appropriate cell lysate or extract.  To date this antibody has shown the ability to recognize over-expressed TMBIM1 but not endogenous protein.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-TMBIM1 antibody (ABIN233805)

Shukla, Fujita, Xiao, Liao, Garfield, Srinivasula: "A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface." in: Apoptosis : an international journal on programmed cell death, (2010) (PubMed).

Target Details for TMBIM1

Target: TMBIM1 (Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1))

Alternative Name: TMBIM1 (TMBIM1 Products)

Synonyms: RECS1 antibody, zgc:103528 antibody, recs1 antibody, mst100 antibody, MGC107973 antibody, TMBIM1 antibody, DKFZp469N0332 antibody, 16.m00782 antibody, LFG3 antibody, MST100 antibody, MSTP100 antibody, 2310061B02Rik antibody, AA960455 antibody, AU024746 antibody, C78899 antibody, Tmbib1 antibody, mKIAA4161 antibody, transmembrane BAX inhibitor motif containing 1 antibody, transmembrane BAX inhibitor motif containing 1a antibody, transmembrane BAX inhibitor motif containing 1 S homeolog antibody, bax inhibitor-1 antibody, Bax inhibitor-1 antibody, Tmbim1 antibody, TMBIM1 antibody, tmbim1a antibody, tmbim1.S antibody, tmbim1 antibody, Chro.60342 antibody, PVX_117470 antibody, BBOV_I000430 antibody, BI-1 antibody

Background: This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. TMBIM1 (Transµembrane BAX inhibitor µotif-containing protein 1) is a member of the 7 TMS (7 transmembrane domains) family of receptors known to mediate the activation of various transcription factors. TMBIM1 is identified as a novel modulator of NF-kB activation.  A drosophila homolog of this protein (dNMDA1 with 40% homology to hTMBIM1) is reported to be unregulated during aging and oxidative stress.
Synonyms: Putative uncharacterized protein TMBIM1

Gene ID: 64114, 50593008

UniProt: Q969X1