Ryanodine Receptor antibody (C-Term)

Catalog No. ABIN225614

The Mouse Monoclonal anti-Ryanodine Receptor antibody has been validated for ELISA, FACS, IF, WB, IHC (fro) and IHC. It is suitable to detect Ryanodine Receptor in samples from Human, Cow, Dog, Mouse, Pig and Rat.

Quick Overview for Ryanodine Receptor antibody (C-Term) (ABIN225614)

Target: Ryanodine Receptor

Reactivity: Human, Cow, Dog, Mouse, Pig, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Ryanodine Receptor antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC)

Product Details anti-Ryanodine Receptor Antibody

Binding Specificity: C-Term

Specificity: Reacts with the C-terminus cytoplasmic domain of ryanodine receptor. Ryanodine receptors have been shown to play critical roles in the intracellular Ca2+ signaling occurring during cell activation in muscle cells and non-muscle cells. Reacts with ryanodine receptor (MW approx. 500kD) isolated from a variety of cell types (e. g. lymphocytes, macrophages, granulocytes, fibroblasts, epithelial, endothelial cells, skeletal muscle, cardiac muscle and brain tissues).

Purification: Purified

Immunogen: Short synthetic polypeptide corresponding to the c-terminal domain of the ryanodine receptor.

Type of Immunogen: Synthetic peptide

Isotype: IgG2b

Application Details

Application Notes: Approved: ELISA (1:1000), Flo (1:500), IF (1:100), IHC, IHC-Fr (1:100), WB (1:100)

Usage: Immunohistology: Use indirect immunofluorescence. Visualization by confocal microscopy is required, as detection by standard fluorescent microscopy will not be adequate to detect the RyR. Additionally, fluorescent, not enzymatic, detection is required.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Ryanodine Receptor

Target: Ryanodine Receptor