FRS2 antibody (pTyr436)

Catalog No. ABIN220203

Product Details anti-FRS2 Antibody

Target: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Binding Specificity: pTyr436

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Detects overexpressed levels of FRS2-alpha only when phosphorylated at Tyr436. Does not cross-react with unrelated tyrosine phosphorylated proteins.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Tyr436 of human FRS2-alpha (KLH coupled).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA, WB (1:1000)

Usage: Suitable for use in Western Blot and ELISA. Western Blot: 1:1000. Incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 % Tween-20 at 4?C with gentle shaking, overnight.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for FRS2

Target: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Alternative Name: FRS2 (FRS2 Products)

Background: Name/Gene ID: FRS2

Synonyms: FRS2, FGFR substrate 2, FRS2A, FGFR signalling adaptor, FGFR-signaling adaptor SNT, FRS2alpha, SNT-1, SNT1, SNT

Gene ID: 10818

UniProt: Q8WU20

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2