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F11R antibody

F11R Reactivity: Mouse WB, FACS, IP, IF Host: Rat Monoclonal BV12 unconjugated
Catalog No. ABIN2191795
  • Target See all F11R Antibodies
    F11R (F11 Receptor (F11R))
    Reactivity
    • 77
    • 49
    • 41
    • 9
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 68
    • 14
    • 14
    • 1
    Rat
    Clonality
    • 60
    • 34
    • 1
    Monoclonal
    Conjugate
    • 44
    • 9
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This F11R antibody is un-conjugated
    Application
    • 59
    • 25
    • 21
    • 15
    • 15
    • 12
    • 7
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)
    Cross-Reactivity (Details)
    Cross reactivity: Human : No
    Sterility
    0.2 μm filtered
    Clone
    BV12
    Isotype
    IgG2a
    Top Product
    Discover our top product F11R Primary Antibody
  • Application Notes
    For flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
    Restrictions
    For Research Use only
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Product should be stored at 4 °C Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
  • Martinez-Estrada, Manzi, Tonetti, Dejana, Bazzoni: "Opposite effects of tumor necrosis factor and soluble fibronectin on junctional adhesion molecule-A in endothelial cells." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 288, Issue 6, pp. L1081-8, (2005) (PubMed).

  • Target
    F11R (F11 Receptor (F11R))
    Alternative Name
    Junctional Adhesion Molecule-A (F11R Products)
    Synonyms
    CD321 antibody, JAM antibody, JAM1 antibody, JAMA antibody, JCAM antibody, KAT antibody, PAM-1 antibody, 9130004G24 antibody, AA638916 antibody, ESTM33 antibody, JAM-1 antibody, JAM-A antibody, Jcam antibody, Jcam1 antibody, Ly106 antibody, Jam1 antibody, F11 receptor antibody, F11R antibody, F11r antibody
    Background
    The monoclonal antibody BV12 recognizes junctional adhesion molecule-A (JAM-A), also known as JAM-1 and the mouse platelet F11-Receptor (F11R), is a cell adhesion molecule (CAM). JAM-A is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular junctions of endothelial cells and epithelial cells. JAM-A belongs together with JAM-B (VE-JAM or JAM- 3) and JAM-C (JAM-2) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. In human JAM-A plays a role in platelet aggregation, secretion, adhesion and spreading. Aliases JAM-1, platelet F11-Receptor, F11R
    Pathways
    Cell-Cell Junction Organization
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