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LY86 antibody

LY86 Reactivity: Mouse FACS, Func Host: Rat Monoclonal MD113 unconjugated
Catalog No. ABIN2191781
  • Target See all LY86 Antibodies
    LY86 (Lymphocyte Antigen 86 (LY86))
    Reactivity
    • 33
    • 19
    • 17
    Mouse
    Host
    • 44
    • 7
    • 4
    Rat
    Clonality
    • 46
    • 9
    Monoclonal
    Conjugate
    • 22
    • 6
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LY86 antibody is un-conjugated
    Application
    • 42
    • 19
    • 13
    • 13
    • 10
    • 10
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Sterility
    0.2 μm filtered
    Clone
    MD113
    Top Product
    Discover our top product LY86 Primary Antibody
  • Application Notes
    For flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.
    Restrictions
    For Research Use only
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Expiry Date
    12 months
  • Nagai, Shimazu, Ogata, Akashi, Sudo, Yamasaki, Hayashi, Iwakura, Kimoto, Miyake: "Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide." in: Blood, Vol. 99, Issue 5, pp. 1699-705, (2002) (PubMed).

  • Target
    LY86 (Lymphocyte Antigen 86 (LY86))
    Alternative Name
    Md-1 (LY86 Products)
    Synonyms
    MD-1 antibody, MMD-1 antibody, dJ80N2.1 antibody, MD1 antibody, LY86 antibody, lymphocyte antigen 86 antibody, LY86 antibody, Ly86 antibody
    Background
    The monoclonal antibody MD113 reacts with mouse MD-1. MD-1 (22-25 kD) is an extracellular protein associated with the extracellular domain of RP105. The latter is a type 1 transmembrane protein with leucine-rich repeats. RP105 is similar to Drosophila Toll. MD-1 associated with RP105 (similar to TLR4/MD-2) appears to be an essential molecule that helps RP105 on B-cells to signal to LPS. The MD113 antibody is antagonistic in LPS-induced B-cell proliferation and B7.2 up-regulation.
    Pathways
    Toll-Like Receptors Cascades
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