PCDH10 antibody (AA 21-120)

Catalog No. ABIN2178728

Product Details anti-PCDH10 Antibody

Target: PCDH10 (Protocadherin 10 (PCDH10))

Binding Specificity: AA 21-120

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDH10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Rat

Predicted Reactivity: Human,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDH10

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-PCDH10 antibody (ABIN2178728)

Deng, Liang, Ying, Dong, Zhang, Yu, Fan, Hao: "Clinical significance of the methylated cytosine-phosphate-guanine sites of protocadherin-10 promoter for evaluating the prognosis of gastric cancer." in: Journal of the American College of Surgeons, Vol. 219, Issue 5, pp. 904-13, (2014) (PubMed).

Target Details for PCDH10

Target: PCDH10 (Protocadherin 10 (PCDH10))

Alternative Name: Protocadherin 10 (PCDH10 Products)

Synonyms: OL-PCDH antibody, PCDH19 antibody, PCDH10 antibody, OLpcad antibody, cadherin antibody, 6430521D13Rik antibody, 6430703F07Rik antibody, OL-pc antibody, mKIAA1400 antibody, RGD1565811 antibody, ZPCR1 antibody, fc56b06 antibody, pcdh10 antibody, pcr1 antibody, wu:fc56b06 antibody, wu:fq40g12 antibody, wu:fq16b02 antibody, protocadherin 10 antibody, protocadherin 10a antibody, protocadherin 10b antibody, PCDH10 antibody, Pcdh10 antibody, pcdh10a antibody, pcdh10b antibody

Background:

Synonyms: PCDH19, OL-PCDH, Protocadherin-1, PCDH1, KIAA14

Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH10 (protocadherin 10), also known as PCDH19 or OL-PCDH, is a 1,040 amino acid single-pass type I membrane protein that contains six cadherin domains and one transmembrane domain. Expressed at moderate levels in brain, ovary and testis and present at lower levels in all other tissues, PCDH10 functions as a calcium-dependent cell-adhesion protein that may function as a tumor suppressor. When underexpressed, PCDH10 is associated with the progression of various carcinomas, including gastric cancer.

Gene ID: 57575

UniProt: Q9P2E7