PCDHB10 antibody (AA 351-450) (AbBy Fluor® 647)

Catalog No. ABIN2178248

Product Details anti-PCDHB10 Antibody (AbBy Fluor® 647)

Target: PCDHB10 (Protocadherin beta 10 (PCDHB10))

Binding Specificity: AA 351-450

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB10 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDHB10

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PCDHB10

Target: PCDHB10 (Protocadherin beta 10 (PCDHB10))

Alternative Name: Pcdhb10 (PCDHB10 Products)

Synonyms: PCDH-BETA10 antibody, PCHB10 antibody, Pcdhb5D antibody, PcdhbJ antibody, protocadherin beta 10 antibody, PCDHB10 antibody, Pcdhb10 antibody

Background:

Synonyms: OTTHUMP00000160026, PCDBA_HUMAN, PCDH BETA10, PCDH-beta-10, PCDHB10, PCHB10,Protocadherin beta-10, Protocadherin beta-10.

Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated a, b and g, all of which contain multiple tandemly-arranged genes. PCDHB10 (protocadherin b10), also known as PCHB10 or PCDH-b10, is an 800 amino acid protein that is one of 16 proteins in the protocadherin b cluster. Unlike the a and g gene clusters, whose genes are spliced to downstream constant-region exons during transcription, members of the b cluster (such as PCDHB10) do not use constant-region exons to produce mRNAs. As a result, each protocadherin b gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB10 is a single-pass type I membrane protein that contains six cadherin domains.