PCDH21 antibody (AA 601-700) (Biotin)

Catalog No. ABIN2178225

Product Details anti-PCDH21 Antibody (Biotin)

Target: PCDH21 (PCDH24) (Protocadherin 21 (PCDH24))

Binding Specificity: AA 601-700

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDH21 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDH21

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PCDH21

Target: PCDH21 (PCDH24) (Protocadherin 21 (PCDH24))

Alternative Name: PCDH21 (PCDH24 Products)

Background:

Synonyms: Protocadherin 21,Cadherin-related family member 1, CDHR1, CDHR1_HUMAN, CORD15, DKFZp434A132, KIAA1775, MT protocadherin, PCDH 21, PCDH21, PCDH21 protein, Photoreceptor cadherin, prCAD, Protocadherin-21, RP65.

Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH21 (protocadherin 21), also known as PRCAD, is an 859 amino acid single-pass membrane protein that localizes to the outer segments of photoreceptor cells and contains six cadherin domains. Existing as multiple alternatively spliced isoforms, PCDH21 functions as a calcium-dependent cell adhesion protein that is thought to be required for the structural integrity of photoreceptor cells and may be involved in the formation and maintenance of neuronal networks.

Gene ID: 92211

UniProt: Q96JP9