MTUS1 antibody (AA 1151-1270)

Catalog No. ABIN2177806

Product Details anti-MTUS1 Antibody

Target: MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))

Binding Specificity: AA 1151-1270

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTUS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MTUS1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MTUS1

Target: MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))

Alternative Name: Mtus1 (MTUS1 Products)

Synonyms: ATBP antibody, ATIP antibody, ICIS antibody, MP44 antibody, MTSG1 antibody, AI481402 antibody, ATBP135 antibody, Atip1 antibody, B430010I23Rik antibody, B430305I03Rik antibody, C85752 antibody, Cctsg1-440 antibody, MD44 antibody, mKIAA1288 antibody, ATIP4 antibody, Atip3b antibody, Mtsg1 antibody, fbx27 antibody, fa17d11 antibody, wu:fa17d11 antibody, wu:fi18f08 antibody, zgc:154168 antibody, microtubule associated scaffold protein 1 antibody, mitochondrial tumor suppressor 1 antibody, microtubule associated scaffold protein 1 L homeolog antibody, microtubule associated tumor suppressor 1 antibody, microtubule associated tumor suppressor 1a antibody, MTUS1 antibody, Mtus1 antibody, mtus1.L antibody, mtus1a antibody

Background:

Synonyms: ATBP, ATIP, ICIS, MP44, MTSG1, Microtubule-associated tumor suppressor 1, AT2 receptor-binding protein, Angiotensin-II type 2 receptor-interacting protein, Mitochondrial tumor suppressor 1, MTUS1, GK1, KIAA1288

Background: Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.

Gene ID: 57509

UniProt: Q9ULD2