LIM Domain Kinase 1/2 (LIMK1/2) (pThr505) antibody (Cy7)
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- Target See all LIM Domain Kinase 1/2 (LIMK1/2) Antibodies
- LIM Domain Kinase 1/2 (LIMK1/2)
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Binding Specificity
- pThr505
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Cy7
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human LIMK1 and LIMK2 around the phosphorylation site of Thr508 and Thr505
- Isotype
- IgG
- Top Product
- Discover our top product LIMK1/2 Primary Antibody
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anti-LIM Domain Kinase 1/2 (LIMK1/2) (pThr505), (pThr508) antibody
LIMK1/2 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- LIM Domain Kinase 1/2 (LIMK1/2)
- Alternative Name
- LIMK1LIMK2 (LIMK1/2 Products)
- Synonyms
- LIMK antibody, LIM domain kinase 2 antibody, LIMK2 antibody
- Background
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Synonyms: LIMK1Thr508, EC 2.7.11.1, LIM domain kinase 1, LIM mot-containing protein kinase, LIMK, LIMK-1, LIMK2, LIMK-2, LIM domain kinase 2, LIMK1_HUMAN.
Background: LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. LIMK1 may be involved in brain development, it is highly expressed in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.
- Gene ID
- 3984
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