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ERI1 antibody (AA 51-150) (Biotin)

ERI1 Reactivity: Mouse ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN2175645
  • Target See all ERI1 Antibodies
    ERI1 (Exoribonuclease 1 (ERI1))
    Binding Specificity
    • 14
    • 9
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivity
    • 45
    • 33
    • 20
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Mouse
    Host
    • 58
    • 2
    Rabbit
    Clonality
    • 58
    • 2
    Polyclonal
    Conjugate
    • 26
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERI1 antibody is conjugated to Biotin
    Application
    • 35
    • 26
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HEXO
    Isotype
    IgG
    Top Product
    Discover our top product ERI1 Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    ERI1 (Exoribonuclease 1 (ERI1))
    Alternative Name
    HEXO (ERI1 Products)
    Synonyms
    THEX1 antibody, thex1 antibody, zgc:110635 antibody, hexo antibody, Eri-1 antibody, 3'HEXO antibody, HEXO antibody, 3'hexo antibody, 3110010F15Rik antibody, Thex1 antibody, eri-1 antibody, RGD1308378 antibody, exoribonuclease 1 antibody, three prime repair exonuclease 1 antibody, exoribonuclease 1 L homeolog antibody, 3'-5' exonuclease eri-1 antibody, ERI1 antibody, CpipJ_CPIJ003945 antibody, eri1 antibody, eri1.L antibody, Eri1 antibody, eri-1 antibody
    Background

    Synonyms: HEXO, THEX1, 3'HEXO, 3'-5' exoribonuclease 1, 3'-5' exonuclease ERI1, Eri-1 homolog, Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-exonuclease 1, Protein 3'hExo, ERI1, 3'EXO

    Background: RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.

    Gene ID
    90459
    UniProt
    Q8IV48
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