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FAM48A/P38IP antibody (AA 21-120) (Biotin)

SUPT20H Reactivity: Human ELISA, IHC (fro), IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN2174051
  • Target See all FAM48A/P38IP (SUPT20H) Antibodies
    FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))
    Binding Specificity
    • 14
    • 2
    • 1
    • 1
    AA 21-120
    Reactivity
    • 19
    • 3
    • 2
    Human
    Host
    • 19
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAM48A/P38IP antibody is conjugated to Biotin
    Application
    • 13
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    Human,Mouse,Rat,Cow
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FAM48A
    Isotype
    IgG
    Top Product
    Discover our top product SUPT20H Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))
    Alternative Name
    FAM48A (SUPT20H Products)
    Synonyms
    SUPT20H antibody, AA667204 antibody, AI450544 antibody, D3Ertd300e antibody, Fam48a antibody, Supt20h antibody, p38IP antibody, RGD1307812 antibody, C13 antibody, C13orf19 antibody, FAM48A antibody, P38IP antibody, SPT20 antibody, bA421P11.4 antibody, SPT20 homolog, SAGA complex component antibody, suppressor of Ty 20 antibody, SUPT20H antibody, Supt20 antibody, Supt20h antibody
    Background

    Synonyms: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.

    Background: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.

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