CTNNA3 antibody (AA 131-230) (AbBy Fluor® 647)
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- Target See all CTNNA3 Antibodies
- CTNNA3 (Catenin (Cadherin-Associated Protein), alpha 3 (CTNNA3))
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Binding Specificity
- AA 131-230
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CTNNA3 antibody is conjugated to AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CTNNA3
- Isotype
- IgG
- Top Product
- Discover our top product CTNNA3 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CTNNA3 (Catenin (Cadherin-Associated Protein), alpha 3 (CTNNA3))
- Alternative Name
- Ctnna3 (CTNNA3 Products)
- Synonyms
- 4930429L08Rik antibody, 4933408A16 antibody, Catna3 antibody, Vr22 antibody, RGD1559455 antibody, RGD1562230 antibody, VR22 antibody, catenin alpha 3 antibody, catenin (cadherin associated protein), alpha 3 antibody, CTNNA3 antibody, Ctnna3 antibody
- Background
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Synonyms: 4930429L08Rik, 4933408A16, Alpha catenin like protein, Alpha T catenin, Alpha T-catenin, Cadherin associated protein, Cadherin-associated protein, Catenin alpha 3, Catenin alpha-3, Catna3, CTNA3_HUMAN, CTNNA3, MGC26194, MGC75041, OTTHUMP00000019684, OTTMUSP00000028119, OTTMUSP00000028120, RP11-433J16.1, VR22.
Background: The catenins are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. alpha T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantally expressed in cardiomyocytes and in the peritubular myoid cells of the testis. alpha T-catenin binds to alpha E-catenin as well as to beta-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for alpha-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer's disease (LOAD) as well as to dilated cardiomyopathy.
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