Claudin 23 antibody (AA 25-81) (Biotin)
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- Target See all Claudin 23 (CLDN23) Antibodies
- Claudin 23 (CLDN23)
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Binding Specificity
- AA 25-81
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Claudin 23 antibody is conjugated to Biotin
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Dog,Cow,Pig,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Claudin 23
- Isotype
- IgG
- Top Product
- Discover our top product CLDN23 Primary Antibody
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- Application Notes
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IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- Claudin 23 (CLDN23)
- Alternative Name
- Claudin 23 (CLDN23 Products)
- Synonyms
- CLDN23 antibody, CLDNL antibody, hCG1646163 antibody, 2310014B08Rik antibody, claudin 23 antibody, si:ch211-95j8.2 antibody, CLDN23 antibody, si:ch211-95j8.2 antibody, Cldn23 antibody
- Background
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Synonyms: 2310014B08Rik, Claudin23, CLDN 23, CLDN23, CLDNL.
Background: The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions. Claudin-23, also known as CLDN23 or CLDNL, is a 292 amino acid multi-pass membrane protein that localizes to cell junctions and belongs to the claudin family. Expressed in stomach and placenta, as well as in germinal center B-cells, claudin-23 is thought to exhibit calcium-dependent cell-adhesion activity through which it plays an essential role in tight junction-specific obliteration of the intercellular space. Human claudin-23 shares 80 % sequence similarity with its mouse counterpart, suggesting a conserved role between species. Overexpression of claudin-23 is associated with colon tumors, implicating claudin-23 as a possible metastasis factor.
- Pathways
- Cell-Cell Junction Organization, Hepatitis C
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