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Claudin 22 (CLDN22) (AA 101-180) antibody (AbBy Fluor® 488)

CLDN22 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN2173197
  • Target See all Claudin 22 (CLDN22) Antibodies
    Claudin 22 (CLDN22)
    Binding Specificity
    • 14
    • 8
    • 7
    • 6
    • 6
    • 1
    AA 101-180
    Reactivity
    • 29
    • 9
    Human
    Host
    • 29
    Rabbit
    Clonality
    • 29
    Polyclonal
    Conjugate
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AbBy Fluor® 488
    Application
    • 15
    • 15
    • 14
    • 12
    • 12
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Claudin 22
    Isotype
    IgG
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  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Claudin 22 (CLDN22)
    Alternative Name
    Claudin 22 (CLDN22 Products)
    Synonyms
    CLDN21 antibody, 2210404A22Rik antibody, 5330431C14Rik antibody, 9530051B05Rik antibody, CLDN22 antibody, claudin 22 antibody, claudin-22 antibody, CLDN22 antibody, Cldn22 antibody, LOC102186369 antibody
    Background

    Synonyms: Claudin-22, CLD22_HUMAN, CLDN21,CLDN22, FLJ51450.

    Background: The claudin superfamily consists of many structurally related proteins that are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. It is suggested that the claudin family of proteins regulate transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specific regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-22, also known as CLDN22, is a 220 amino acid member of the claudin family that participates in tight junction-specific obliteration of the intercellular space through calcium-independent cell-adhesion activity.

    Pathways
    Cell-Cell Junction Organization, Hepatitis C
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