CLDN10 antibody (AA 151-228) (AbBy Fluor® 488)

Catalog No. ABIN2173101

Product Details anti-CLDN10 Antibody (AbBy Fluor® 488)

Target: CLDN10 (Claudin 10 (CLDN10))

Binding Specificity: AA 151-228

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLDN10 antibody is conjugated to AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Claudin 10

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CLDN10

Target: CLDN10 (Claudin 10 (CLDN10))

Alternative Name: Claudin 10 (CLDN10 Products)

Synonyms: si:busm1-52i16.3 antibody, si:dz52i16.3 antibody, CLDN10 antibody, DKFZp469F1626 antibody, CPETRL3 antibody, OSP-L antibody, 6720456I16Rik antibody, Cldn10a antibody, Cldn10b antibody, D14Ertd728e antibody, claudin 10a antibody, claudin 10 antibody, cldn10a antibody, CLDN10 antibody, Cldn10 antibody

Background:

Synonyms: Claudin-10, Claudin10, CLD10_HUMAN, CLDN 10, CLDN10, CLDN10 protein, CPETRL 3, CPETRL3, HGNC:2033, OSP L, OSP like protein, OSP-like protein, OSPL.

Background: The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecules. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-10 is a 228 amino acid multi-pass membrane protein that belongs to the claudin family and plays an important role in cell-adhesion activity and tight junction-specific events.

Pathways: Hepatitis C