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FAT4 antibody (AA 4351-4450) (Biotin)

FAT4 Reactivity: Mouse, Rat ELISA, WB, IHC (fro), IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN2172808
  • Target See all FAT4 Antibodies
    FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))
    Binding Specificity
    • 14
    • 5
    • 2
    • 1
    AA 4351-4450
    Reactivity
    • 18
    • 14
    • 14
    Mouse, Rat
    Host
    • 29
    • 3
    Rabbit
    Clonality
    • 29
    • 3
    Polyclonal
    Conjugate
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAT4 antibody is conjugated to Biotin
    Application
    • 20
    • 13
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CDHF14
    Isotype
    IgG
    Top Product
    Discover our top product FAT4 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))
    Alternative Name
    CDHF14 (FAT4 Products)
    Synonyms
    CDHF14 antibody, CDHR11 antibody, FAT-J antibody, FATJ antibody, NBLA00548 antibody, 6030410K14Rik antibody, 9430004M15 antibody, FAT atypical cadherin 4 antibody, FAT4 antibody, Fat4 antibody
    Background

    Synonyms: Cadherin family member 14, CDHF14, FAT tumor suppressor homolog 4, Fat-like cadherin protein FAT-J, FAT4, FAT4_HUMAN, FATJ, hFat4, Nbla00548, Protocadherin Fat 4.

    Background: The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT4 (FAT tumor suppressor homolog 4), also known as FAT-J, CDHF14 or CDHR11, is a 4,981 amino acid single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins and localizes to the primary cilia of kidney. Widely expressed, FAT4 contains thirty-four cadherin domains, six EGF-like domains and two laminin G-like domains. FAT4 may function in the regulation of planar cell polarity.

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