Calmodulin 1 antibody (AA 81-152)

Catalog No. ABIN2172206

Product Details anti-Calmodulin 1 Antibody

Target: Calmodulin 1 (Calm1)

Binding Specificity: AA 81-152

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calmodulin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody may detect CAMI, CAM2, CAM3

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Calmodulin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Calmodulin 1

Target: Calmodulin 1 (Calm1)

Alternative Name: Calmodulin (Calm1 Products)

Synonyms: AI256814 antibody, AI327027 antibody, AI461935 antibody, AL024000 antibody, CaM antibody, Calm antibody, CaMI antibody, CALML2 antibody, CAMI antibody, CPVT4 antibody, DD132 antibody, LQT14 antibody, PHKD antibody, caM antibody, calm1 antibody, calm2-a antibody, calm2-b antibody, calm2a antibody, calml2 antibody, cami antibody, dd132 antibody, 3909 antibody, CAM antibody, CG8472 antibody, Cal antibody, Cal49A antibody, CalA antibody, Cam1 antibody, D-CaM antibody, DmCaM antibody, DmCalm antibody, Dmel\CG8472 antibody, anon-EST:Posey59 antibody, cam antibody, dCaM antibody, l(2)03909 antibody, l(2)3909 antibody, lincRNA.S2634 antibody, calmodulin 1 antibody, calmodulin 2 antibody, calmodulin 1 (phosphorylase kinase, delta) L homeolog antibody, Calmodulin antibody, Calm1 antibody, Calm2 antibody, CALM1 antibody, calm1.L antibody, Cam antibody

Background:

Synonyms: CALM 1, CALM 2, CALM 3, CALM, CALM1, CALM2, CALM3, CALML2, Calmodulin 1, Calmodulin1, CAM 1, CAM 2, CAM 3, CaM, CAM I, CAM1, CAM2, CAM3, CAMB, CAMC, CAMI, CAMIII, DD132, PHKD, Phosphorylase kinase delta, Phosphorylase kinase delta subunit, Calmodulin1, Calmodulin 1, Calmodulin-1, Calmodulin2, Calmodulin 2, Calmodulin-2, Calmodulin3, Calmodulin 3, Calmodulin-3.

Background: Calmodulin consists of two glycoproteins, 34 and 39 kDa, sometimes designated epithelial antigen, epithelial specific antigen, and epithelial glycoprotein. The glycoproteins are located on the cell membrane surface and in the cytoplasm of virtually all epithelial cells with the exception of most squamous epithelia, hepatocytes, renal proximal tubular cells, gastric parietal cells and myoepithelial cells. Epithelial Calmodulin is found in the large majority of adenocarcinomas of most sites (50-100 % in various studies, as well as neuroendocrine tumours, including small cell carcinoma. Renal cell carcinoma and hepatocellular carcinoma stain in about 30 % of the cases. Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin Ca(2+) complex are a number of protein kinases and phosphatases. Calmodulin has four functional calcium binding sites.

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling