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BRIP1 antibody (pSer990)

BRIP1 Reactivity: Human, Mouse WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2170674
  • Target See all BRIP1 Antibodies
    BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))
    Binding Specificity
    • 14
    • 9
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    pSer990
    Reactivity
    • 58
    • 35
    • 14
    • 12
    • 12
    • 12
    • 12
    • 12
    Human, Mouse
    Host
    • 54
    • 3
    • 1
    Rabbit
    Clonality
    • 55
    • 3
    Polyclonal
    Conjugate
    • 19
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This BRIP1 antibody is un-conjugated
    Application
    • 43
    • 22
    • 22
    • 12
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This phosphorylation site is homologous to that of Ser921 in Bovine.
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Cow,Sheep
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human BRIP1 around the phosphorylation site of Ser990
    Isotype
    IgG
    Top Product
    Discover our top product BRIP1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))
    Alternative Name
    BRIP1 (BRIP1 Products)
    Synonyms
    MGC68622 antibody, BRIP1 antibody, fancj antibody, si:ch211-158l18.1 antibody, BACH1 antibody, FANCJ antibody, OF antibody, 3110009N10Rik antibody, 8030460J03Rik antibody, Bach1 antibody, FACJ antibody, Fancj antibody, BRCA1 interacting protein C-terminal helicase 1 antibody, BRCA1 interacting protein C-terminal helicase 1 L homeolog antibody, Brip1 antibody, brip1.L antibody, BRIP1 antibody, brip1 antibody
    Background

    Synonyms: OF, BACH1, FANCJ, Fanconi anemia group J protein, Protein FACJ, ATP-dependent RNA helicase BRIP1, BRCA1-associated C-terminal helicase 1, BRCA1-interacting protein C-terminal helicase 1, BRCA1-interacting protein 1, BRIP1

    Background: DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.

    Gene ID
    83990
    UniProt
    Q9BX63
    Pathways
    DNA Damage Repair
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