CX3CR1 antibody (Extracellular Domain)

Catalog No. ABIN213589

Product Details anti-CX3CR1 Antibody

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Binding Specificity: Extracellular Domain

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CX3CR1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human CX3CR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human (100%) Gorilla, Gibbon, Monkey (95%) Marmoset, Mouse, Panda (84%).

Purification: Immunoaffinity purified

Immunogen: Synthetic 19 amino acid peptide from 3rd extracellular domain of human CX3CR1. Percent identity with other species by BLAST analysis: Human (100%), Gorilla, Gibbon, Monkey (95%), Marmoset, Mouse, Panda (84%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 - 10 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5-10 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Alternative Name: CX3CR1 (CX3CR1 Products)

Synonyms: CCRL1 antibody, CMKBRL1 antibody, CMKDR1 antibody, GPR13 antibody, GPRV28 antibody, V28 antibody, Rbs11 antibody, C-X3-C motif chemokine receptor 1 antibody, chemokine (C-X3-C motif) receptor 1 antibody, CX3C chemokine receptor 1 antibody, CX3CR1 antibody, Cx3cr1 antibody, LOC100559882 antibody

Background: Name/Gene ID: CX3CR1
Subfamily: Chemokine
Family: GPCR

Synonyms: CX3CR1, Beta chemokine receptor-like 1, C-X3-C CKR-1, Chemokine (C-X3-C) receptor 1, CMKBRL1, CMK-BRL-1, CMKDR1, CMK-BRL1, CX3C chemokine receptor 1, Fkn receptor, GPR13, GPRV28, Fractalkine receptor, G protein-coupled receptor v28, G-protein coupled receptor 13, V28, Chemokine c-x3-c receptor 1, G protein-coupled receptor 13

Gene ID: 1524

Pathways: Cellular Response to Molecule of Bacterial Origin