PDE3A antibody (Internal Region)

Catalog No. ABIN213555

Product Details anti-PDE3A Antibody

Target: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse, Monkey, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE3A antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human PDE3A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Mouse, Rat, Horse, Opossum (100%) Chicken (88%).

Purification: Immunoaffinity purified

Immunogen: Synthetic 17 amino acid peptide from internal region of human PDE3A. Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Mouse, Rat, Horse, Opossum (100%), Chicken (88%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (20 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 20 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PDE3A

Target: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Alternative Name: PDE3A (PDE3A Products)

Synonyms: PDE3A antibody, Pde3a antibody, si:dkey-48h7.2 antibody, A930022O17Rik antibody, C87899 antibody, RNPDE3A antibody, CGI-PDE antibody, CGI-PDE A antibody, CGI-PDE-A antibody, phosphodiesterase 3A antibody, phosphodiesterase 3A, cGMP-inhibited antibody, cGMP-inhibited 3',5'-cyclic phosphodiesterase A antibody, phosphodiesterase 3A, cGMP inhibited antibody, PDE3A antibody, Pde3a antibody, LOC100540515 antibody, pde3a antibody

Background: Name/Gene ID: PDE3A
Subfamily: PDE - cAMP/cGMP dual-specific, cGMP-inhibited
Family: Phosphodiesterase

Synonyms: PDE3A, CGI-PDE-A, HcGIP2, Phosphodiesterase 3a, Phosphodiesterase isoform 3a, CGI-PDE, CGI-PDE A, CGIP2, HPDE-3A, Phosphodiesterase type 3A

Gene ID: 5139

Pathways: cAMP Metabolic Process