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PDE8B antibody (Internal Region)

PDE8B Reactivity: Human, Horse, Monkey, Bat IHC (p), IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN213535
  • Target See all PDE8B Antibodies
    PDE8B (phosphodiesterase 8B (PDE8B))
    Binding Specificity
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    Internal Region
    Reactivity
    • 14
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Horse, Monkey, Bat
    Host
    • 20
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    This PDE8B antibody is un-conjugated
    Application
    • 13
    • 10
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC)
    Brand
    IHC-plus™
    Specificity
    Human PDE8B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Predicted Reactivity
    Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Bat, Elephant, Horse (100%) Pig, Opossum (94%) Mouse, Platypus (88%) Rat, Dog (82%).
    Purification
    Immunoaffinity purified
    Immunogen
    Synthetic 17 amino acid peptide from internal region of human PDE8B. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Bat, Elephant, Horse (100%), Pig, Opossum (94%), Mouse, Platypus (88%), Rat, Dog (82%).

    Type of Immunogen: Synthetic peptide
    Top Product
    Discover our top product PDE8B Primary Antibody
  • Application Notes
    Approved: IHC, IHC-P (10 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS, less than 0.1 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PDE8B (phosphodiesterase 8B (PDE8B))
    Alternative Name
    PDE8B (PDE8B Products)
    Synonyms
    PDE8B antibody, ADSD antibody, PPNAD3 antibody, B230331L10Rik antibody, C030047E14Rik antibody, RNPDE8B antibody, phosphodiesterase 8B antibody, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B antibody, PDE8B antibody, LOC100468338 antibody, pde8b antibody, Pde8b antibody
    Background
    Name/Gene ID: PDE8B
    Subfamily: PDE - cAMP-specific, high affinity
    Family: Phosphodiesterase

    Synonyms: PDE8B, ADSD, HsPDE8B, PPNAD3, Phosphodiesterase 8B
    Gene ID
    8622
    Pathways
    Negative Regulation of Hormone Secretion, cAMP Metabolic Process
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