Lysine (K)-Specific Methyltransferase 2A (KMT2A) (AA 3084-3959) antibody
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- Target See all Lysine (K)-Specific Methyltransferase 2A (KMT2A) Antibodies
- Lysine (K)-Specific Methyltransferase 2A (KMT2A)
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Binding Specificity
- AA 3084-3959
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Specificity
- Recognizes the C-terminal proteolytic fragment of human MLL (MLLC), Mr ~180kD. Species cross-reactivity: Human and mouse.
- Purification
- Protein G purified
- Immunogen
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MBP fusion protein corresponding to residues 3084-3959 of human mixed lineage leukemia (MLL).
Type of Immunogen: Fusion protein - Clone
- 4H354
- Isotype
- IgG1
- Top Product
- Discover our top product KMT2A Primary Antibody
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- Application Notes
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Approved: IP, WB (0.1 - 1 μg/mL)
Usage: Suitable for use in Western Blot and Immunoprecipitation. Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunoprecipitation: Reported by an independent laboratory to immunoprecipitate MLLC from nuclear extracts. The N-terminal fragment, MLLN (300kD), is also co-immunoprecipitated by this antibody. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide, 30 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- Lysine (K)-Specific Methyltransferase 2A (KMT2A)
- Alternative Name
- KMT2A / MLL (KMT2A Products)
- Synonyms
- 6430520K01 antibody, ALL-1 antibody, All1 antibody, Cxxc7 antibody, HRX antibody, HTRX1 antibody, Mll antibody, Mll1 antibody, mKIAA4050 antibody, lysine (K)-specific methyltransferase 2A antibody, Kmt2a antibody
- Background
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Name/Gene ID: KMT2A
Synonyms: KMT2A, ALL1, CDK6/MLL fusion protein, FLJ11783, HRX, HTRX, HTRX1, Lysine N-methyltransferase 2A, MLL1A, MLL/GAS7, MLL1, ALL-1, MLL, MLL/GAS7 fusion protein, TRX1, WDSTS, Trithorax-like protein, Zinc finger protein HRX, CXXC7, MLL-AF4 der(11) fusion protein, MLL/GMPS fusion protein, TET1-MLL - Gene ID
- 4297
- UniProt
- Q03164
- Pathways
- Warburg Effect
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