CXCR4 antibody (AA 1-14)
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- Target See all CXCR4 Antibodies
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Binding Specificity
- AA 1-14
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CXCR4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- Specificity
- CXCR4 associates with the surface CD4-gp120 complex before HIV enters target cells. CXCR4 messenger RNA levels correlated with HIV-1 permissiveness in diverse human cell types. Blocks HIV-1 and HIV-2 fusion and infection of human target cells. The amino-terminal domain and the second extracellular loop of CXCR4 serve as HIV binding sites.
- Purification
- Purified
- Immunogen
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Peptide corresponding to amino acids 1 to 14 of human CXCR4 (3,9).
Type of Immunogen: Synthetic peptide - Isotype
- IgG
- Top Product
- Discover our top product CXCR4 Primary Antibody
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- Application Notes
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Approved: ICC (10 μg/mL), IP (10 μg/mL), WB (1 - 2 μg/mL)
Usage: Suitable for use in Western Blot, Immunoprecipitation and Immunocytochemistry. Western Blot: 1-2 μg/mL. Immunoprecipitation: 10 μg/mL. Immunocytochemistry: 10 μg/mL. Positive control: HeLa whole cell lysate. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS. No preservative added.
- Preservative
- Azide free
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- Target
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- Alternative Name
- CXCR4 (CXCR4 Products)
- Background
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Name/Gene ID: CXCR4
Subfamily: Chemokine
Family: GPCR
Synonyms: CXCR4, CD184, CD184 antigen, Cmkar4, Cxc chemokine receptor 4, CXCR-4, CXC-R4, D2S201E, FB22, Fusin, HM89, LCR1, NPY3R, NPYRL, NPYY3R, Npyy3, HSY3RR, SDF-1 receptor, WHIM, C-x-c chemokine receptor 4, LESTR, Neuropeptide Y receptor Y3, NPYR - Gene ID
- 7852
- UniProt
- P61073
- Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
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