MAP3K8 antibody (AA 396-445)

Catalog No. ABIN202595

Product Details anti-MAP3K8 Antibody

Target: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Binding Specificity: AA 396-445

Reactivity: Human, Rat, Cow, Monkey, Horse, Dog, Rabbit, Bat, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K8 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human MAP3K8

Predicted Reactivity: Percent identity by BLAST analysis: Human, Rat, Dog, Bovine, Horse (100%) Mouse (92%) Chicken (84%).

Purification: Protein A purified

Immunogen: Synthetic peptide located between aa396-445 of human MAP3K8 (P41279, NP_005195). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Galago, Marmoset, Rat, Dog, Bovine, Bat, Hamster, Elephant, Panda, Horse, Platypus (100%), Mouse, Guinea pig, Xenopus (92%), Lizard (91%), Opossum, Turkey, Chicken (84%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (2.5 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for MAP3K8

Target: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Alternative Name: MAP3K8 / TPL2 (MAP3K8 Products)

Synonyms: MAP3K8 antibody, COT antibody, EST antibody, ESTF antibody, MEKK8 antibody, TPL2 antibody, Tpl-2 antibody, c-COT antibody, Cot antibody, Cot/Tpl2 antibody, Est antibody, Estf antibody, Tpl2 antibody, D17TPL2 antibody, mitogen-activated protein kinase kinase kinase 8 antibody, MAP3K8 antibody, map3k8 antibody, Map3k8 antibody

Background: Name/Gene ID: MAP3K8
Subfamily: MAP3K
Family: Protein Kinase

Synonyms: MAP3K8, C-COT, Cancer Osaka thyroid oncogene, COT, Ewing sarcoma transformant, EST, MEKK8, Proto-oncogene c-Cot, TPL2, Tumor progression locus 2, Protein kinase cot, Tpl-2, ESTF

Gene ID: 1326

NCBI Accession: NP_005195

UniProt: P41279

Pathways: PI3K-Akt Signaling, TCR Signaling