GJA8 antibody (AA 290-440)

Catalog No. ABIN200662

Product Details anti-GJA8 Antibody

Target: GJA8 (Gap Junction Protein, alpha 8, 50kDa (GJA8))

Binding Specificity: AA 290-440

Reactivity: Human, Mouse, Rat, Sheep

Host: Mouse

Clonality: Monoclonal

Conjugate: This GJA8 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Specificity: Specific for Connexin 50. It does not cross-react with other Connexin proteins. Anti-Connexin 50 recognizes an epitope in the cytoplasmic (carboxy) tail located between residues 290-440. Reacts with Connexin 50 from sheep, human, mouse, rat and probably other species. Tested in a wide variety of tissues including lens, cornea and heart valve.

Purification: Gel filtration

Immunogen: Urea/alkali stripped sheep lens membranes.

Type of Immunogen: Membrane extract

Clone: C6

Isotype: IgM kappa

Application Details

Application Notes: Approved: ELISA (0.1 - 1 μg/mL), IF (10 - 50 μg/mL), IP, WB (1 - 5 μg/mL)

Usage: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunoprecipitation. ELISA: 0.1-1.0 μg/mL. Western Blot: 1-5 μg/mL. Immunofluorescence 10-50 μg/mL. Immunoprecipitation: 5-10 μg.

Comment:

Target Species of Antibody: Sheep

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for GJA8

Target: GJA8 (Gap Junction Protein, alpha 8, 50kDa (GJA8))

Alternative Name: GJA8 / CX50 / Connexin 50 (GJA8 Products)

Background: Name/Gene ID: GJA8
Subfamily: Connexin
Family: Ion Channel

Synonyms: GJA8, Connexin 49, Connexin-50, CAE, CX50, Gap junction alpha-8 protein, Gap junction protein alpha 8, Lens fiber protein MP70, MP70, CAE1, Cell surface glycoprotein, Connexin 50, CZP1

Gene ID: 2703

UniProt: P48165