Histone H2B antibody (AA 2-125)

Catalog No. ABIN618456

Product Details anti-Histone H2B Antibody

Target: Histone H2B

Binding Specificity: AA 2-125

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H2B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Histone H2B type 1-C/E/F/G/I protein (2-125AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Histone H2B

Target: Histone H2B

Alternative Name: HIST1H2BC (Histone H2B Products)

Background:

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.

Aliases: H2BC4 antibody, H2BFL antibody, HIST1H2BC, antibody, H2BC6 antibody, H2BFH antibody, HIST1H2BE, antibody, H2BC7 antibody, H2BFG antibody, HIST1H2BF, antibody, H2BC8 antibody, H2BFA antibody, HIST1H2BG, antibody, H2BC10 antibody, H2BFK antibody, HIST1H2BIHistone H2B type 1-C/E/F/G/I antibody, Histone H2B.1 A antibody, Histone H2B.a antibody, H2B/a antibody, Histone H2B.g antibody, H2B/g antibody, Histone H2B.h antibody, H2B/h antibody, Histone H2B.k antibody, H2B/k antibody, Histone H2B.l antibody, H2B/l antibody

UniProt: P62807