EIF3I antibody (AA 1-323) (FITC)
-
- Target See all EIF3I Antibodies
- EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))
-
Binding Specificity
- AA 1-323
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This EIF3I antibody is conjugated to FITC
-
Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Eukaryotic translation initiation factor 3 subunit I protein (1-323AA)
- Isotype
- IgG
- Top Product
- Discover our top product EIF3I Primary Antibody
-
-
- Application Notes
- Optimal working concentration should be determinde by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))
- Alternative Name
- EIF3I (EIF3I Products)
- Synonyms
- EIF3S2 antibody, PRO2242 antibody, TRIP-1 antibody, TRIP1 antibody, eIF3-beta antibody, eIF3-p36 antibody, 36kDa antibody, D4Ertd632e antibody, Eif3s2 antibody, Trip1 antibody, eIF-3-beta antibody, eIF3 p36 antibody, eif3s2 antibody, hm:zehn0464 antibody, wu:fb62b08 antibody, zgc:56211 antibody, zgc:77823 antibody, CaO19.2967 antibody, eIF-3 39 kDa subunit homolog antibody, eIF3i antibody, eif3-beta antibody, eif3-p36 antibody, eif3i antibody, pro2242 antibody, trip-1 antibody, trip1 antibody, eukaryotic translation initiation factor 3 subunit I antibody, eukaryotic translation initiation factor 3, subunit I antibody, Eukaryotic Initiation Factor antibody, Eukaryotic translation initiation factor 3 subunit I antibody, translation initiation factor eIF3 subunit i antibody, eukaryotic translation initiation factor 3 subunit I L homeolog antibody, EIF3I antibody, Eif3i antibody, eif-3.I antibody, eIF3i antibody, eif3i antibody, TIF34 antibody, eif3i.L antibody
- Background
-
Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Aliases: eIF-3-beta antibody, eIF3 beta antibody, eIF3 p36 antibody, eIF3-beta antibody, eIF3-p36 antibody, eIF3i antibody, EIF3I_HUMAN antibody, EIF3S2 antibody, EIF3S2, formerly antibody, Eukaryotic translation initiation factor 3 subunit 2 antibody, Eukaryotic translation initiation factor 3 subunit 2 beta antibody, Eukaryotic translation initiation factor 3 subunit I antibody, eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD antibody, eukaryotic translation initiation factor 3, subunit 2 beta, 36 kDa antibody, eukaryotic translation initiation factor 3, subunit 2, formerly antibody, eukaryotic translation initiation factor 3, subunit I antibody, Predicted protein of HQ2242 antibody, PRO2242 antibody, TGF beta receptor interacting protein 1 antibody, TGF-beta receptor-interacting protein 1 antibody, TGFbeta receptor interacting protein 1 antibody, TGFbeta receptor-interacting protein 1 antibody, TRIP 1 antibody, TRIP-1 antibody, TRIP1 antibody
- UniProt
- Q13347
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Ribonucleoprotein Complex Subunit Organization, Synthesis of DNA
-