CD101 antibody

Catalog No. ABIN1981871

Product Details anti-CD101 Antibody

Target: CD101

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD101 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: The mouse monoclonal antibody BB27 recognizes an extracellular epitope of CD101, a 140 kDa disulfide-bonded homodimeric protein expressed on activated T cells, and some other cell types, such as granulocytes and cells of the monocyte/macropgage lineage.

Cross-Reactivity (Details): Human

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: Human thymic clone B12

Clone: BB27

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Do not use after expiration date stamped on vial label.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

References for anti-CD101 antibody (ABIN1981871)

Grassi, Dezutter-Dambuyant, McIlroy, Jacquet, Yoneda, Imamura, Boumsell, Schmitt, Autran, Debré, Hosmalin: "Monocyte-derived dendritic cells have a phenotype comparable to that of dermal dendritic cells and display ultrastructural granules distinct from Birbeck granules." in: Journal of leukocyte biology, Vol. 64, Issue 4, pp. 484-93, (1998) (PubMed).

Target Details for CD101

Target: CD101

Alternative Name: CD101 (CD101 Products)

Synonyms: Gm1016 antibody, Gm734 antibody, Igsf2 antibody, EWI-101 antibody, IGSF2 antibody, V7 antibody, CD101 molecule antibody, CD101 antigen antibody, CD101 antibody, Cd101 antibody

Background: CD101 Molecule,CD101 is a type I transmembrane glycoprotein, which forms disulfide-linked homodimers. It is expressed on activated T cells, as well as on granulocytes, monocytes, dendritic cells or mucosal T cells. It plays a major role in the activation of T cells by skin dendritic cells. Function of CD101 has not been fully elucidated, but in mice its knock-out results in liver autoimmune disease induced by Novosphingobium aromaticivorans.,IGSF2, V7, EWI-101

Gene ID: 9398

UniProt: Q93033