STRADA antibody (C-Term)

Catalog No. ABIN1981302

Product Details anti-STRADA Antibody

Target: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Binding Specificity: AA 303-346, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRADA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STRADA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 303-346 amino acids from the C-terminal region of human STRADA.

Clone: RB47810

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IF: 1:25. WB: 1:1000. IHC-P: 1:100. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-STRADA antibody (ABIN1981302)

Sun, Li, Chen, Huang, Chen, Cui, Liu, Thrasher, Li: "GSK-3? controls autophagy by modulating LKB1-AMPK pathway in prostate cancer cells." in: The Prostate, (2015) (PubMed).

Target Details for STRADA

Target: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Alternative Name: STRADA (STRADA Products)

Synonyms: fj99g05 antibody, zgc:56109 antibody, wu:fj99g05 antibody, lyk5 antibody, LYK5 antibody, NY-BR-96 antibody, PMSE antibody, STRAD antibody, Stlk antibody, Lyk5 antibody, 2610019A05Rik antibody, 6030402H20Rik antibody, AI480680 antibody, E130112C09Rik antibody, STE20-related kinase adaptor alpha antibody, ste20-related kinase adaptor alpha antibody, STRADA antibody, strada antibody, Strada antibody

Background: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

Molecular Weight: 48369

Gene ID: 92335

UniProt: Q7RTN6

Pathways: AMPK Signaling