CLDN3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
IF: 1:100. WB: 1:1000. IHC: 1:50-1:100
Restrictions
For Research Use only
Format
Liquid
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Storage
4 °C,-20 °C
Peacock, Keen, Inglehearn: "Analysis of a human gene homologous to rat ventral prostate.1 protein." in: Genomics, Vol. 46, Issue 3, pp. 443-9, (1998) (PubMed).
Katahira, Sugiyama, Inoue, Horiguchi, Matsuda, Sugimoto: "Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo." in: The Journal of biological chemistry, Vol. 272, Issue 42, pp. 26652-8, (1997) (PubMed).
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity).