PHKG1 antibody

Catalog No. ABIN1944825

Product Details anti-PHKG1 Antibody

Target: PHKG1 (phosphorylase Kinase, gamma 1 (Muscle) (PHKG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHKG1 antibody is un-conjugated

Application: Western Blotting (WB)

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Storage: 4 °C,-20 °C

References for anti-PHKG1 antibody (ABIN1944825)

Hillier, Fulton, Fulton, Graves, Pepin, Wagner-McPherson, Layman, Maas, Jaeger, Walker, Wylie, Sekhon, Becker, OLaughlin, Schaller, Fewell, Delehaunty, Miner, Nash, Cordes, Du, Sun, Edwards et al.: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).

Wehner, Kilimann: "Human cDNA encoding the muscle isoform of the phosphorylase kinase gamma subunit (PHKG1)." in: Human genetics, Vol. 96, Issue 5, pp. 616-8, (1996) (PubMed).

Target Details for PHKG1

Target: PHKG1 (phosphorylase Kinase, gamma 1 (Muscle) (PHKG1))

Alternative Name: PHKG1 (PHKG1 Products)

Background: Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity).

Molecular Weight: 45024 Da

Gene ID: 5260

UniProt: Q16816

Pathways: Cellular Glucan Metabolic Process