AVPR2
Reactivity: Mouse
WB, ELISA, IF (cc), IF (p), IHC (fro), ICC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
IF: 1:100. WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Storage
4 °C,-20 °C
North, Fay, Longo, Du: "Expression of all known vasopressin receptor subtypes by small cell tumors implies a multifaceted role for this neuropeptide." in: Cancer research, Vol. 58, Issue 9, pp. 1866-71, (1998) (PubMed).
Fay, Du, Yu, North: "Evidence for expression of vasopressin V2 receptor mRNA in human lung." in: Peptides, Vol. 17, Issue 3, pp. 477-81, (1996) (PubMed).
Wildin, Antush, Bennett, Schoof, Scott: "Heterogeneous AVPR2 gene mutations in congenital nephrogenic diabetes insipidus." in: American journal of human genetics, Vol. 55, Issue 2, pp. 266-77, (1994) (PubMed).
Seibold, Brabet, Rosenthal, Birnbaumer: "Structure and chromosomal localization of the human antidiuretic hormone receptor gene." in: American journal of human genetics, Vol. 51, Issue 5, pp. 1078-83, (1992) (PubMed).
Birnbaumer, Seibold, Gilbert, Ishido, Barberis, Antaramian, Brabet, Rosenthal: "Molecular cloning of the receptor for human antidiuretic hormone." in: Nature, Vol. 357, Issue 6376, pp. 333-5, (1992) (PubMed).
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption.