This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MPP7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-36 amino acids from the N-terminal region of human MPP7.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Wells, Fawcett, Traweger, Yamanaka, Goudreault, Elder, Kulkarni, Gish, Virag, Lim, Colwill, Starostine, Metalnikov, Pawson: "A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells." in: Cell, Vol. 125, Issue 3, pp. 535-48, (2006) (PubMed).
Katoh, Katoh: "Identification and characterization of human MPP7 gene and mouse Mpp7 gene in silico." in: International journal of molecular medicine, Vol. 13, Issue 2, pp. 333-8, (2004) (PubMed).
Deloukas, Earthrowl, Grafham, Rubenfield, French, Steward, Sims, Jones, Searle, Scott, Howe, Hunt, Andrews, Gilbert, Swarbreck, Ashurst, Taylor, Battles, Bird, Ainscough, Almeida, Ashwell, Ambrose et al.: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, (2004) (PubMed).
Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.