REG3A antibody (C-Term)

Catalog No. ABIN1944738

Product Details anti-REG3A Antibody

Target: REG3A (Regenerating Islet-Derived 3 alpha (REG3A))

Binding Specificity: AA 129-163, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REG3A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This REG3A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 129-163 amino acids from the C-terminal region of human REG3A.

Clone: RB48666

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-REG3A antibody (ABIN1944738)

Lasserre, Simon, Ishikawa, Diriong, Nguyen, Christa, Vernier, Brechot: "Structural organization and chromosomal localization of a human gene (HIP/PAP) encoding a C-type lectin overexpressed in primary liver cancer." in: European journal of biochemistry / FEBS, Vol. 224, Issue 1, pp. 29-38, (1994) (PubMed).

Dusetti, Frigerio, Fox, Swallow, Dagorn, Iovanna: "Molecular cloning, genomic organization, and chromosomal localization of the human pancreatitis-associated protein (PAP) gene." in: Genomics, Vol. 19, Issue 1, pp. 108-14, (1994) (PubMed).

Itoh, Teraoka: "Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP)." in: Biochimica et biophysica acta, Vol. 1172, Issue 1-2, pp. 184-6, (1993) (PubMed).

Orelle, Keim, Masciotra, Dagorn, Iovanna: "Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases." in: The Journal of clinical investigation, Vol. 90, Issue 6, pp. 2284-91, (1993) (PubMed).

Lasserre, Christa, Simon, Vernier, Bréchot: "A novel gene (HIP) activated in human primary liver cancer." in: Cancer research, Vol. 52, Issue 18, pp. 5089-95, (1992) (PubMed).

Target Details for REG3A

Target: REG3A (Regenerating Islet-Derived 3 alpha (REG3A))

Alternative Name: REG3A (REG3A Products)

Synonyms: HIP antibody, HIP/PAP antibody, INGAP antibody, PAP antibody, PAP-H antibody, PAP1 antibody, PBCGF antibody, REG-III antibody, REG3 antibody, AV063448 antibody, Pap2 antibody, PapII antibody, PTP antibody, REG3G antibody, regenerating family member 3 alpha antibody, regenerating islet-derived 3 alpha antibody, REG3A antibody, Reg3a antibody

Background: Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.

Molecular Weight: 19395

Gene ID: 5068

UniProt: Q06141