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HLA-DP/DR antibody (FITC)

HLA-DP/DR Reactivity: Human FACS Host: Mouse Monoclonal MEM-136 FITC
Catalog No. ABIN192205
  • Target See all HLA-DP/DR products
    HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))
    Reactivity
    • 16
    • 5
    Human
    Host
    • 16
    Mouse
    Clonality
    • 16
    Monoclonal
    Conjugate
    • 5
    • 4
    • 3
    • 2
    • 2
    This HLA-DP/DR antibody is conjugated to FITC
    Application
    • 16
    • 8
    • 8
    • 5
    • 3
    • 1
    Flow Cytometry (FACS)
    Specificity
    The antibody MEM-136 recognizes a common extracellular epitope on beta-chain of human HLA-DR and HLA-DP. It reacts with alpha/beta dimer as well as with dissociated beta-subunit. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).
    Cross-Reactivity (Details)
    Human
    Purification
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    PHA-activated peripheral blood lymphocytes.
    Clone
    MEM-136
    Isotype
    IgG1
  • Application Notes
    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Comment

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Reconstitution
    No reconstitution is necessary.
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Avoid prolonged exposure to light.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Koch, Staffler, Hüttinger, Hilgert, Prager, Cerný, Steinlein, Majdic, Horejsí, Stockinger: "T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density." in: International immunology, Vol. 11, Issue 5, pp. 777-86, (1999) (PubMed).

  • Target
    HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))
    Alternative Name
    HLA-DR+DP (HLA-DP/DR Products)
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