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Laminin 5 antibody

LN-5 Reactivity: Human, Rat WB, IHC (fro), EIA Host: Mouse Monoclonal 6F12 unconjugated
Catalog No. ABIN191945
  • Target See all Laminin 5 (LN-5) products
    Laminin 5 (LN-5)
    Reactivity
    • 9
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 5
    • 4
    Mouse
    Clonality
    • 5
    • 4
    Monoclonal
    Conjugate
    • 9
    This Laminin 5 antibody is un-conjugated
    Application
    • 8
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    Characteristics
    Synonyms: Laminin-5
    Purification
    Protein A Chromatography
    Immunogen
    Human Laminin 5 beta 3 chain
    Clone
    6F12
    Isotype
    IgG
  • Application Notes
    Western blot. ELISA (coating antibody in Sandwich ELISA). Immunohistochemistry on Cryosections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore in aqua bidest to initial volume.
    Buffer
    PBS, pH 7.4
    Storage
    4 °C/-20 °C
    Storage Comment
    Store lyophilized at 2-8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    Expiry Date
    12 months
  • Drumea-Mirancea, Wessels, Müller, Essl, Eble, Tolosa, Koch, Reinhardt, Sixt, Sorokin, Stierhof, Schwarz, Klein: "Characterization of a conduit system containing laminin-5 in the human thymus: a potential transport system for small molecules." in: Journal of cell science, Vol. 119, Issue Pt 7, pp. 1396-405, (2006) (PubMed).

    Amano, Akutsu, Ogura, Nishiyama: "Increase of laminin 5 synthesis in human keratinocytes by acute wound fluid, inflammatory cytokines and growth factors, and lysophospholipids." in: The British journal of dermatology, Vol. 151, Issue 5, pp. 961-70, (2004) (PubMed).

    Sasaki, Amano, Nishiyama, Nakayama, Burgeson, Nakajima: "Expression of laminin 5, and collagen IV and VII in bullous pemphigoid skin." in: Archives of dermatological research, Vol. 290, Issue 5, pp. 283-5, (1998) (PubMed).

    Barnstable, Bodmer, Brown, Galfre, Milstein, Williams, Ziegler: "Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis." in: Cell, Vol. 14, Issue 1, pp. 9-20, (1978) (PubMed).

  • Target
    Laminin 5 (LN-5)
    Alternative Name
    Laminin 5 (LN-5 Products)
    Background
    Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. laminin 5 is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: Laminin-5
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