DNAJC13 antibody (N-Term)

Catalog No. ABIN1888158

Product Details anti-DNAJC13 Antibody

Target: DNAJC13 (DnaJ heat shock protein family (Hsp40) member C13 (DNAJC13))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJC13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): DNAJC13 antibody is predicted to not cross-react with other DNAJC family members.

Purification: Affinity chromatography purified via peptide column

Immunogen: DNAJC13 antibody was raised against an 18 amino acid peptide near the amino terminus of human DNAJC13.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for DNAJC13

Target: DNAJC13 (DnaJ heat shock protein family (Hsp40) member C13 (DNAJC13))

Alternative Name: DNAJC13 (DNAJC13 Products)

Synonyms: RME8 antibody, D030002L11Rik antibody, Gm1124 antibody, RME-8 antibody, Rme8 antibody, mKIAA0678 antibody, DnaJ heat shock protein family (Hsp40) member C13 antibody, dnaJ homolog subfamily C member 13 antibody, DNAJC13 antibody, LOC100167963 antibody, LOC100640734 antibody, Dnajc13 antibody

Background: DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C.elegans.It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system.Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles.DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor.
Synonyms: DNAJ homolog subfamily C member 13, receptor-mediated endocytosis 8, RME8

NCBI Accession: NP_056083