MEX3D antibody (Center)
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- Target See all MEX3D Antibodies
- MEX3D (Mex-3 Homolog D (MEX3D))
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Binding Specificity
- Center
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MEX3D antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- 15 amino acid peptide from near the center of human Rkhd1.
- Top Product
- Discover our top product MEX3D Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Handling Advice
- Avoid freezing and thawing repeatly.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- Target
- MEX3D (Mex-3 Homolog D (MEX3D))
- Alternative Name
- Rkhd1 (MEX3D Products)
- Synonyms
- RKHD1 antibody, MEX3D antibody, rkhd1 antibody, mex3 antibody, tino antibody, rnf193 antibody, ok/sw-cl.4 antibody, MEX-3D antibody, MEX3 antibody, OK/SW-cl.4 antibody, RNF193 antibody, TINO antibody, BC059858 antibody, Rkhd1 antibody, mex-3 RNA binding family member D antibody, mex-3 RNA binding family member D L homeolog antibody, mex3 RNA binding family member D antibody, MEX3D antibody, mex3d.L antibody, mex3d antibody, Mex3d antibody
- Background
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Rkhd1, also known as TINO or MEX3D is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module.MEX3 proteins, including Rkhd1, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway.These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms.Rkhd1 binds to the AU-rich element in the 3'-untranslated region of Bcl-2 mRNA and is thought to be a negative regulator of Bcl-2 expression.Rkhd3 and Rkhd4, but not Rkhd1, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
Synonyms: RING finger and KH domain-containing protein 1, MEX3D, TINO, RING finger protein 193, RNF193 - UniProt
- Q86XN8
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