NSRP1
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice
Avoid freezing and thawing repeatly.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Target
NSRP1
(Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))
CCDC55, also known as Nuclear speckle-related protein 70 (NSrp70), was initially identified by the NIH Mammalian Gene Collection.Nuclear speckles are known to be the storage sites of mRNA splicing regulators.CCDC55 has been suggested to modulate alternative pre-mRNA splicing in vivo.It co-localizes and physically interacts with the SR proteins SC35 and ASF/SF2, essential splicing factors which are required for constitutive splicing and can regulate alternative mRNA splicing.Loss of CCDC55 in mice leads to early embryonic lethality highlights the importance of the functional role of CCDC55. Synonyms: Coiled-coil domain-containing protein 55, HSPC095, NSrp70