fb83e10 antibody, im:7160995 antibody, wu:fb83e10 antibody, FBXL6 antibody, FBL6 antibody, FBL6A antibody, PP14630 antibody, AU021795 antibody, Fbl6 antibody, F-box and leucine-rich repeat protein 6 antibody, F-box and leucine rich repeat protein 6 antibody, fbxl6 antibody, FBXL6 antibody, Fbxl6 antibody
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box.The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats.Alternative splicing of this gene generates 2 transcript variants.[provided by RefSeq]