SUCLA2 antibody (AA 138-386)

Catalog No. ABIN1886025

Product Details anti-SUCLA2 Antibody

Target: SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))

Binding Specificity: AA 138-386

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUCLA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 138 and 386 of human SUCLA2

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for SUCLA2

Target: SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))

Alternative Name: SUCLA2 (SUCLA2 Products)

Synonyms: 4930547K18Rik antibody, A-BETA antibody, MTDPS5 antibody, SCS-betaA antibody, SCS antibody, succinate-Coenzyme A ligase, ADP-forming, beta subunit antibody, succinate-CoA ligase ADP-forming beta subunit antibody, Sucla2 antibody, SUCLA2 antibody

Background: Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit.The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle.SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA.Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome.A pseudogene of this gene has been found on chromosome 6.[provided by RefSeq]

Molecular Weight: 50 kDa

Gene ID: 8803

NCBI Accession: NM_003850, NP_003841