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HRAS antibody (AA 111-176)
HRAS
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HRAS Antibody
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Target
See all HRAS Antibodies
HRAS
(HRas proto-oncogene, GTPase (HRAS))
Binding Specificity
All epitopes for HRAS antibodies
AA 111-176
Reactivity
All reactivities for HRAS antibodies
Human
Host
All hosts for HRAS antibodies
Rabbit
Clonality
All clonalities for HRAS antibodies
Polyclonal
Conjugate
All conjugates for HRAS antibodies
This HRAS antibody is un-conjugated
Application
All applications for HRAS antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Purification
Purified by antigen-affinity chromatography.
Immunogen
Synthetic peptide contain a sequence corresponding to a region within amino acids 111 and 176 of H-Ras
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Alternatives
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Application Details
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Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.500 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for HRAS
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Target
HRAS
(HRas proto-oncogene, GTPase (HRAS))
Alternative Name
H-Ras (HRAS Products )
Synonyms
C-BAS/HAS antibody, C-H-RAS antibody, C-HA-RAS1 antibody, CTLO antibody, H-RASIDX antibody, HAMSV antibody, HRAS1 antibody, K-RAS antibody, N-RAS antibody, RASH1 antibody, hras antibody, zgc:110250 antibody, HRAS antibody, H-RAS antibody, c-H-ras antibody, H-Ras antibody, K-Ras antibody, hras1 antibody, rash1 antibody, ras antibody, N-Ras antibody, c-bas/has antibody, H-ras antibody, Ha-ras antibody, Harvey-ras antibody, Hras-1 antibody, Kras2 antibody, c-Ha-ras antibody, c-rasHa antibody, hrasl antibody, zgc:110734 antibody, HRas proto-oncogene, GTPase antibody, v-Ha-ras Harvey rat sarcoma viral oncogene homolog a antibody, neuroblastoma RAS viral (v-ras) oncogene homolog pseudogene antibody, Harvey rat sarcoma viral oncogene homolog L homeolog antibody, Harvey rat sarcoma viral oncogene homolog antibody, Harvey rat sarcoma virus oncogene antibody, NRAS proto-oncogene, GTPase antibody, -Ha-ras Harvey rat sarcoma viral oncogene homolog b antibody, HRAS antibody, hrasa antibody, LOC733587 antibody, Hras antibody, hras.L antibody, hras antibody, NRAS antibody, hrasb antibody
Background
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses.The products encoded by these genes function in signal transduction pathways.These proteins can bind GTP and GDP, and they have intrinsic GTPase activity.This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus.Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities.Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma.Multiple transcript variants, which encode different isoforms, have been identified for this gene.[provided by RefSeq]
Molecular Weight
21 kDa
Gene ID
3265
NCBI Accession
NM_005343 , NP_005334
Pathways
p53 Signaling , MAPK Signaling , RTK Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Hepatitis C , Autophagy , Signaling Events mediated by VEGFR1 and VEGFR2 , Signaling of Hepatocyte Growth Factor Receptor , Regulation of long-term Neuronal Synaptic Plasticity , VEGF Signaling , BCR Signaling
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