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UCHL5 antibody
UCHL5
Reactivity: Human
WB
Host: Mouse
Monoclonal
854CT5-5-6
unconjugated
Product Details anti-UCHL5 Antibody
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Target
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UCHL5
(Ubiquitin Carboxyl-terminal Hydrolase L5 (UCHL5))
Reactivity
All reactivities for UCHL5 antibodies
Human
Host
All hosts for UCHL5 antibodies
Mouse
Clonality
All clonalities for UCHL5 antibodies
Monoclonal
Conjugate
All conjugates for UCHL5 antibodies
This UCHL5 antibody is un-conjugated
Application
All applications for UCHL5 antibodies
Western Blotting (WB)
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen
Purified His-tagged UCH37 protein was used to produced this monoclonal antibody.
Clone
854CT5-5-6
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
WB: 1:2000-1:4000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
References for anti-UCHL5 antibody (ABIN1882286)
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Yao, Song, Xu, DeMartino, Florens, Swanson, Washburn, Conaway, Conaway, Cohen : "Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1. " in: Nature cell biology , Vol. 8 , Issue 9 , pp. 994-1002 , (2006 ) (PubMed ).
Target Details for UCHL5
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Target
UCHL5
(Ubiquitin Carboxyl-terminal Hydrolase L5 (UCHL5))
Alternative Name
UCH37 (UCHL5) (UCHL5 Products )
Synonyms
zgc:85615 antibody, wu:fj17f09 antibody, uch37 antibody, cgi-70 antibody, DKFZp459M0513 antibody, 5830413B11Rik antibody, Uch37 antibody, CGI-70 antibody, INO80R antibody, UCH-L5 antibody, UCH37 antibody, ubiquitin carboxyl-terminal hydrolase L5 antibody, ubiquitin C-terminal hydrolase L5 antibody, ubiquitin C-terminal hydrolase L5 L homeolog antibody, ubiquitin carboxyl-terminal esterase L5 antibody, uchl5 antibody, UCHL5 antibody, uchl5.L antibody, Uchl5 antibody
Background
Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex, however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.
Molecular Weight
37607
NCBI Accession
NP_001186190 , NP_001186191 , NP_001186192 , NP_057068
UniProt
Q9Y5K5
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