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EGFR antibody (C-Term)

Name: EGFR antibody (C-Term)
SKU: ABIN1882237
Price: 451 USD
Availability: InStock

EGFR Reactivity: Human WB, IHC (p) Host: Mouse Monoclonal 688CT33-1-3 unconjugated

All lanes : Anti-EGFR Antibody (C-term) at 1:8000 dilution Lane 1: A549 whole cell lysate Lane 2: PC-3 whole cell lysate Lane 3: A431 whole cell lysate Lane 4: MDA-MB-231 whole cell lysate Lysates/proteins at 20 μg per lane. (EGFR antibody (C-Term))

Immunohistochemical analysis of paraffin-embedded R. (EGFR antibody (C-Term))

IHC (p)

All lanes : Anti-EGFR Antibody (C-term) at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 g per lane. (EGFR antibody (C-Term))

Immunohistochemical analysis of paraffin-embedded H. (EGFR antibody (C-Term))

IHC (p)

Immunohistochemical analysis of paraffin-embedded M. (EGFR antibody (C-Term))

IHC (p)

6 images

Catalog No. ABIN1882237

Datasheet as PDF

Target See all EGFR Antibodies

EGFR (Epidermal Growth Factor Receptor (EGFR))
Binding Specificity
40

39

31

30

29

27

26

26

21

21

19

16

16

16

15

15

15

15

11

11

10

10

9

9

8

8

7

6

5

5

5

4

4

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

2
AA 1163-1191, C-Term
Reactivity
744

293

283

26

26

24

19

14

8

3

2

2

1

1

1

1

1

1
Human
Host
580

165

14

13

5

1

1
Mouse
Compatible Secondaries
Clonality
534

240

2
Monoclonal
Conjugate
412

58

29

22

19

16

15

15

15

15

15

11

10

10

10

10

10

10

10

10

10

8

8

5

4

4

4

4

4

1

1

1

1

1

1
This EGFR antibody is un-conjugated
Application
536

246

150

145

129

102

101

94

82

49

37

35

34

18

11

7

6

4

4

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen

This EGFR antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1163-1191 amino acids from the C-terminal region of human EGFR.

Clone

688CT33-1-3

Isotype

IgG1

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anti-Epidermal Growth Factor Receptor (EGFR) (AA 1021-1210) antibody
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Application Notes

WB: 1:8000. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Expiry Date

6 months
Target

EGFR (Epidermal Growth Factor Receptor (EGFR))

Alternative Name

EGFR (EGFR Products)

Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Molecular Weight

134277

NCBI Accession

NP_005219, NP_958439, NP_958440, NP_958441

UniProt

P00533

Pathways

NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins