Acetylcholinesterase antibody (C-Term)

Catalog No. ABIN1882203

Product Details anti-Acetylcholinesterase Antibody

Target: Acetylcholinesterase (AChE)

Binding Specificity: AA 587-611, C-Term

Reactivity: Human, Rat, Mouse, Green Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Acetylcholinesterase antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, Rb

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This ACHE antibody is generated from mouse immunized with a KLH conjugated synthetic peptide between 587-611 amino acids from the C-terminal region of human ACHE.

Clone: 684CT8-3-4

Isotype: IgG1

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Acetylcholinesterase antibody (ABIN1882203)

Tang, Ma, Yang, Huang, Ge, Sui, Wei, Cao: "The feasibility study of extradural nerve anastomosis technique for canine bladder reinnervation after spinal cord injury." in: The journal of spinal cord medicine, Vol. 39, Issue 6, pp. 679-685, (2018) (PubMed).

Karpel, Ben Aziz-Aloya, Sternfeld, Ehrlich, Ginzberg, Tarroni, Clementi, Zakut, Soreq: "Expression of three alternative acetylcholinesterase messenger RNAs in human tumor cell lines of different tissue origins." in: Experimental cell research, Vol. 210, Issue 2, pp. 268-77, (1994) (PubMed).

Soreq, Ben-Aziz, Prody, Seidman, Gnatt, Neville, Lieman-Hurwitz, Lev-Lehman, Ginzberg, Lipidot-Lifson: "Molecular cloning and construction of the coding region for human acetylcholinesterase reveals a G + C-rich attenuating structure." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 24, pp. 9688-92, (1991) (PubMed).

Target Details for Acetylcholinesterase

Target: Acetylcholinesterase (AChE)

Alternative Name: ACHE (AChE Products)

Background: Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.

Molecular Weight: 67796

NCBI Accession: NP_000656, NP_001269378, NP_056646

UniProt: P22303

Pathways: Skeletal Muscle Fiber Development